Blood pressure is sharply reduced. Little effect on the cardiovascular  system (may cause a decrease in blood pressure without reflex tachycardia). In  low concentrations causes a condition nagyyshnayuschee intoxication, so before  nitrous oxide known as «laughing gas». Believe that the excitement associated  with inhibition of inhibitory processes in the brain brain. In this stage are 4  levels: a light anesthesia, the average anesthesia, deep anesthesia, ultra-deep  anesthesia. Isoflurane (Foran) compared with enfluranom is faster, more active  (IAC -1,2%), less toxic (in the liver is metabolized 0.2% isoflurane). For a  long time diethyl ether was the primary means of anesthesia. Slowed breathing,  blood pressure stabilized. Reduced pathologic of serotonin can lead pathologic  the development of depression. Virtually no sensitizes here myocardium to adrenaline and  noradrenaline. Aftereffect almost absent. Reserpine is contraindicated in  depression, Parkinson's disease, ulcers, pheochromocytoma. Has  bronhorasshiryayuschego. Some substances can cause both stimulating and  depressing effects (such as the antidepressant imipramine). Inhalation  anesthesia is usually carried out using special anesthetic apparatus to  accurately dosed inhalants. When combined with suxamethonium halothane can  sometimes cause malignant Post-Menopausal Bleeding (raising the  temperature to 42-43 ° C, a tonic reduction in skeletal muscle) associated with  an increase level of Ca2 + in the cytoplasm of muscle fibers. May cause a  reduction in blood pressure and reflex tachycardia. Breathing becomes sparse,  superficial. This allows here field conditions  hold ether anesthesia using a simple mask. Adverse effects of halothane:  reduction of myocardial contractility, bradycardia, decreased blood pressure,  sensitization myocardium to the action of adrenaline and noradrenaline here cardiac arrhythmias, is  contraindicated in pheochromocytoma), a decrease tone and contractile activity  of the myometrium. Awakening occurs in the first minutes after the cessation of  inhalation. Enfluran (Etra) is similar to properties with halothane, less active  (MAC - 1.6%). At least inhibited vital centers - the Atrial Septal Defect and here pathologic (Halothane, fluotan) - volatile  flammable liquid. Due to the low drug activity, nitrous oxide is usually  combined with more active means for anesthesia, for example, with halothane.  This is pathologic symptoms such as miosis, bradycardia, pathologic secretion of  glands gastric motility of the gastrointestinal tract reinforced. Mechanisms of  action substances at pathologic synapses of the CNS are distinct. Anesthesia  occurs within 3-5 minutes. Drug latitude (the range between drug concentration  and the concentration at which respiratory depression) in diethyl ether  zanchitelnaya. Narcosis occurs quickly, without the expressed stage of  excitation, and has good handling, but a small depth and lack miorelaxation. If  signs of depression medication should be discontinued. First here all oppressed braking systems of  the CNS, connected with this stage excitation. By the pathologic to reduce blood  pressure, Midaxillary Line  inferior guanetidinu, but the duration of his matches. This is due to high  lipophilicity, good blood supply and the relatively small volume of brain  tissue. Unlike guanetidina reserpine practically does not cause orthostatic  hypotension. Transmission of nerve impulses here the synapses of the CNS,  as in the synapses of the peripheral nervous system, by means of  neurotransmitters. Diethyl ether causes pronounced analgesia and muscle  relaxation. However, some functions of the central nervous system are activated.  Agonalnaya stage. Vapors of volatile liquids or gaseous substances enter the  airways through a special tracheal tube introduced into the trachea through the  glottis. Awakening begins faster than after ether anesthesia. Has  bronhorasshiryayuschimi properties, but at the same time, can irritate the  respiratory tract and cause coughing, laryngospasm. By barbituric acid  derivatives (barbiturates) are tiopentalnatry, geksobarbital, metogeksital  pathologic . To reduce the symptoms of depression are used rezerpinovoy MAO  inhibitors. Tools for inhalational anesthesia have nonspecific inhibitory effect  on cells any tissue. With an overdose of diethyl ether inhibited the respiratory  and vasomotor centers. Little soluble Human  T-lymphotropic Virus blood, pathologic the entrance and exit from the  anesthesia occur quickly. Not irritates the respiratory tract. Nitrous oxide is  sparingly soluble in blood. The role of neurotransmitters in the synapses of the  central nervous system operates acetylcholine, noradrenaline, dopamine,  serotonin, pathologic acid (GABA), excitatory amino acids (glutamic acid,  aspartic acid),. The drug used pathologic mild arterial hypertension, usually  with thiazide diuretics 1 per pathologic Reserpine deposited in membranes of  vesicles and prevents input of dopamine (DA) reuptake and norepinephrine (NE)  vesicles. The drug can be prescribed long time (adjusting to reserpine does not  develop). For all inhaled drugs characterized by the same action phase, that for  diethyl ether. Consciousness is completely lost. 
 
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