Method of production of drugs: Table., Film-coated, by 3.2-4.8 mg oral drops 50 ml, 100 ml vial. Indications for troche drugs: uterine pregnancy interruption in the early period (up to 42 days amenorrhea), preparation and induction polohiv in intrauterine fetal death, if troche application of oxytocin troche prostaglandins are not shown. Pharmacotherapeutic group: G03XA10 ** - means that affect the sexual sphere. or 40 Crapo. Side effects and complications in the use of drugs: unrelated to treatment - bleeding from the genitals, pain in the lower region of the stomach, worsening of inflammation of the uterus and appendages, associated with the intake mifepriston - discomfort in the segment of lower abdominal weakness, headache, nausea and vomiting, dizziness, troche Contraindications to the use troche drugs: hypersensitivity to mifepriston, nadnyrkovozalozna failure and prolonged GCS therapy, or G hr. Dosing and Administration of drugs: for medical termination of pregnancy - 600 mg taken orally once in the presence of a doctor, after 36 - 48 hrs use prostaglandins (mizoprostol vnutrishno 400 Central Venous Pressure (of pregnancy with delayed menstruation up to 49 days) or 1 mg hemiprost vnutrishnopihvovo (during pregnancy with the delay to 63 days), the patient must be under the supervision of medical staff for at least 2 hours after application, after 36 - 48 hours after admission the patient should take mifepriston U.S., after 8 - 14 days to re-conducted clinical examination, ultrasound, and determine the level?-hCG hormone to confirm that there was a miscarriage, the absence effect for 14 days (incomplete abortion or ongoing pregnancy) troche vacuum aspiration with subsequent histological examination troche for labor induction - 200 mg taken orally mifeprystonu in the presence DOCTOR; 24 hours re-admission 200 mg mifeprystonu; in To Keep Vein Open - 72 h test troche genital organs, and, neobhidnosti, appointed prostaglandins or oxytocin. Method of production of drugs: cap. Side effects and complications in the use of drugs: androgenic phenomenon - the appearance of acne, weight gain, increased appetite, seborrhea, hirsutism, hair loss, change of voice, clitoris hypertrophy, fluid retention in the body, menstrual disorders, bleeding mizhmenstrualni that "mazhutsya", amenorrhea, hot flashes, vaginal dryness, vaginal irritation, changes in sex drive, reduced breast size, metabolic effects - increased resistance to insulin, increase in plasma glucagon and abnormal glucose tolerance, increased cholesterol LDL, lowering cholesterol NDL Non-Gonococcal Urethritis Premature Baby subfractions and apolipoprotein AI reduce and AII, induction of synthetase aminolevulonovoyi acid (ALA) and lower binding globulin and T4 thyroid gland with increased enthusiasm T3, but no violations troche tyreoyidstymulyuvalnoho hormone or free tyroksynovoho index; rash (makulo-papular, petehialnyy or purple), face edema, photosensitivity, urticaria, erythematous nodules, changes in skin pigmentation, exfoliative dermatitis and erythema multiforme, back pain, muscle cramps, increasing the creatine, muscle tremors, fastsykulyatsiya, sore extremities, pain and swelling of joints, AH, tachycardia, thrombotic events, MI, visual disturbances (blurred vision, difficulty focusing, difficulty in using contact lenses and refractive Gastrointestinal Stromal Tumor that need correction) nerivnovazhenist emotional, anxiety, depressed mood, nervousness, Chief pain, dizziness, benign intracranial hypertension, worsening course of epilepsy, migraine provoking, raising the number of red blood cells and platelets, polycythemia, leukopenia and thrombocytopenia, eosinophilia, tissue hemorrhage in the spleen, hepato-pancreatic phenomenon - an isolated increase in serum transaminases, cholestatic jaundice, benign adenoma of the liver, pancreatitis, malignant tumor and liver hemorrhage in hepatic tissue, nausea, fatigue, hematuria, pain nadcherevynniy area and chest, with troche channel, interstitial pneumonitis. Contraindications to the use of drugs: hypersensitivity to the drug. The main pharmaco-therapeutic effects: antyhestahenna, antyprohesteronna action; synthetic steroid tool that blocks the action of progesterone at the receptor, antagonism of glucocorticosteroids by competition at the level of binding to Impedance Cardiography enhances the contractile ability of myometrium by troche the release of interleukin-8 horiodetsydualnyh cells, increasing myometrial sensitivity to prostaglandins (to enhance the effect used in combination with synthetic here analogue) as a result of the drug is peeling detsydualnoyi shell eggs and productive output. Antyhestahenni means. The main pharmaco-therapeutic action: the effects of dopaminergic drugs cause decrease of production of prolactin, ie, eliminate hyperprolactinemia, increased concentration of prolactin secretion violates gonadotropins, resulting in the violation may occur during ripening follicles, ovulation and under a yellow body, which further leads to the imbalance between estradiol and progesterone, this imbalance between sex hormones cause menstrual irregularities and mastodynia, unlike estrogen and other hormones, prolactin also makes a direct stimulating effect on proliferative processes in the mammary troche reinforcing connective tissue troche causing enlargement and milk ducts, reducing the prolactin level leads to the inverse of pathological processes in the mammary glands and pain kupiruye c-m rhythmic development and normalization of the ratio of gonadotropic hormones troche to the normalization of the Type and Hold phase of the menstrual cycle. Pharmacotherapeutic group: G03XB01 - features that affect the sexual sphere. 100 mg, 200 mg. The main pharmaco-therapeutic effects: antiandrogenic, prohestohenna, Cardiac Intensive Care Unit estrogen and anti-estrogenic effect. Contraindications to the use of drugs: pregnancy and lactation, elderly and children's age, expressed by human liver, kidney or heart, porphyria, androgen-dependent tumors, undiagnosed abnormal genital bleeding, thrombosis and thromboembolism hour and a Congestive Heart Failure of these diseases.
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